High-throughput Screening

High-throughput Screening

Our research focuses on the development of ultrahigh-throughput platforms for rapid screening, selection, and evolution of enzymes and biomolecular systems.

Research Focus
– Flow cytometry-based screening
– Microfluidic screening platforms
– Rapid identification of improved variants
– Functional selection of enzymes and biomolecules

Overview
We develop high-throughput experimental platforms that enable efficient screening of large molecular libraries. By combining flow cytometry and microfluidics, we accelerate discovery and optimization of biomolecules with enhanced catalytic activity, selectivity, and stability.

These approaches support both fundamental biochemical studies and applied biotechnological development.

Approaches and Methods
– Fluorescence-activated cell sorting (FACS)
– Droplet microfluidics
– Library screening and selection
– Quantitative activity analysis

Applications
– Directed evolution of enzymes
– Discovery of improved biocatalysts
– Functional screening of protein variants
– Biotechnology and biomedical research

Collaborations
We welcome collaborations in screening technologies, enzyme evolution, and microfluidic platform development.